Spektroskopske metode za detekciju kemijskih bojnih agenasa

undergraduate thesis

• Title (english): Spectroscopic Methods for Chemical Warfare Agents Detection
• Author: Alen Turkanović
• Mentor: Tatjana Gazivoda Kraljević (mentor)
• Mentor: Valentina Ključarić (mentor)
• Committee member: Ivica Smojver (predsjednik povjerenstva)
• Committee member: Tatjana Gazivoda Kraljević (član povjerenstva)
• Committee member: Valentina Ključarić (član povjerenstva)
• Granter: University of Zagreb; (Croatian Defence Academy "Dr. Franjo Tuđman"); Zagreb
• Defense date and country: 2018-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Interdisciplinary Natural Sciences

Abstract

U ovom radu prikazani su kemijski bojni agensi s kemijskog i toksikološkog gledišta. Opisane su spektroskopske (1H i 13C NMR) i spektrometrijske (MS) metode za detekciju i određivanje strukture kemijskih bojnih agenasa. Prikazane su postojeće toksikološke podjele bojnih otrova (BO), posebice prema načinu toksičnog djelovanja. Također je za određene bojne otrove pojašnjeno što su, te koja su to fizikalno-kemijska svojstva bojnih otrova i na što utječu. Spektri 1H i 13C NMR odabranih vrsta bojnih agenasa (Tabun, Sarin, Soman, VX, Iperit, dušični iperit, cijanovodična kiselina, difosgen, kloracetofenon, CS) predviđeni su programom Chem Draw 8.0 i NMRDB. Asigniranje 1H i 13C NMR spektara provedeno je na temelju kemijskih pomaka, multipliciteta i intenziteta signala te sprega spin-spin. Maseni spektri određenih bojnih otrova dostupnih u literaturi također su asignirani na osnovi odnosa m/z molekulskog i osnovnog iona. Zapažanja, aktualnosti bojnih otrova današnjice, realna opasnost od istih te potreba za metodama detekcije i identifikacije opisani su u zaključku ovog rada.

Abstract (english)

This paper presents the chemical warfare agents from a chemical and toxicological viewpoint. Spectroscopic (1H i 13C NMR) and spectrometric (MS) methods for detection and structure determination of chemical warfare agents have been described. Existing toxicological divisions of war gases are shown, in particular by the method of toxicity. Furthermore, the physical and chemical properties of chemical warfare agents and their affect are also described. The 1H and 13C NMR spectra of the selected chemical warfare agents (Tabun, Sarin, Soman, VX, Iperit, nitrogen iperit, cyanide acid, diphosgene, chloroacetophenone, CS) were predicted by Chem Draw 8.0 and NMRDB. Assignments of 1H and 13C NMR spectra were performed on the basis of chemical shifts, multiplicity and signal intensity and spin-spin coupling. The mass spectra of corresponding war gases available in the literature are also assayed based on the m/z molecular and base number relationship. Observations, the relevance of present-day war gases, the real threat of them and the need for detection and identification methods are described in the conclusion of this paper.

• Keywords: kemijski bojni agensi; detekcija; spektroskopske metode; spektrometrijske metode
• Keywords (english): chemical warfare agents; detection; spectroscopic methods; spectrometric methods
• Language: croatian
• URN:NBN: urn:nbn:hr:249:292147
• Study programme: Title: Military Engineering; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica inženjer/inženjerka vojnog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica inženjer/inženjerka vojnog inženjerstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Closed access
• Created on: 2019-10-25 10:02:12